Since speaking with Uprooted Concepts, Robinson, who self-administered plant compounds, including macro cannabinoid doses, underwent new tes

CBG ultimately liberates killer T cells, which can increase the effectiveness of PD-1 blockers and other anti-cancer drugs.

But overactive orexin converts the endocannabinoid into one paricular metabolite known as 2-AGp. 

And out of the three proteins, endocannabinoid release requires either gamma and beta together or alpha-synuclein by itself.

Effects might cancel each other out, which might explain why it takes such a large dose of CBD to protect the endocannabinoid system.

Cannabinoid receptors could not explain why cows given anandamide preferred sweeter water.

And a new National Institute of Health (NIH) study discusses how one transmitter in the ECS — anandamide — helps maintain balance and regrow

They identified seven mechanisms that the cannabinoid, CBC, depends on to protect and regenerate the nervous system.

A new discovery connects the cannabinoid 1 receptor with a different receptor that, in part, controls dopamine during Parkinson’s Disease.

Arachidonic-serine (ARA-s), for example, is a special negatively charged endocannabinoid that regulates our heart’s electrical wave.

The theory suggests that CBD relies on deactivating a receptor known as GPR55 to treat epilepsy and seizure related illnesses.

A recent study further mapped out how Fenofibrate crosstalks with endocannabinoids by chronically agonizing the PPAR receptor.

Doctors once thought muscular pain was psychosomatic, but statin medications likely deplete cannabinoid receptor dysfunction.

And the tumour microenvironment, consisting of an endocannabinoid system, unfortunately, hijacks the immune system.

Discoveries tied together over two centuries now map an extensive endocannabinoid system found in nearly every animal.

These interactions helped the researchers target NSE’s therapeutic potential as a PPAR-y agonist within the endocannabinoidome.